An Unusual Aquaporin-Like Metalloid Boric Acid Channel in Arabidopsis
نویسندگان
چکیده
منابع مشابه
NIP6;1 is a boric acid channel for preferential transport of boron to growing shoot tissues in Arabidopsis.
Boron (B) in soil is taken up by roots through NIP5;1, a boric acid channel, and is loaded into the xylem by BOR1, a borate exporter. Here, the function of Arabidopsis thaliana NIP6;1, the most similar gene to NIP5;1, was studied. NIP6;1 facilitates the rapid permeation of boric acid across the membrane but is completely impermeable to water. NIP6;1 transcript accumulation is elevated in respon...
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Boric acid (BA), widely used for both medicinal and nonmedicinal purposes, was known to adversely affect reproduction and fertility in rodents. NIOSH, in evaluating the literature prior to writing a Criteria Document, asked NIEHS to perform an RACB study on BA to generate both structural and functional data to be used for setting exposure criteria (Fail et al., Fundam Appl Toxicol 17:225-239 [1...
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Boric acid and its chemical relatives are pesticides that are derived from the element boron. Boron rarely occurs alone and is typically found in combination with other elements; common combinations are boric acid or borates.1 Unlike many pesticides which are synthetic compounds,2 boric acid and related pesticides are naturally occurring compounds.1 Boron compounds are widely found in rivers, s...
متن کاملIdentification and characterization of an Arabidopsis mutant with altered localization of NIP5;1, a plasma membrane boric acid channel, reveals the requirement for D-galactose in endomembrane organization.
Endomembrane organization is important for various aspects of cell physiology, including membrane protein trafficking. To explore the molecular mechanisms regulating the trafficking of plasma membrane-localized proteins in plants, we screened for Arabidopsis mutants with defective localization of green fluorescent protein (GFP)-nodulin 26-like intrinsic protein (NIP)5;1. Fluorescence imaging-ba...
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We report 7 infants suffering from seizures induced by chronic boric acid ingestion. The boric acid was given by dipping a soother in a proprietary borax and honey mixture. The babies have remained well since the mixture was withheld.
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2013
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2012.11.3500